> For the complete documentation index, see [llms.txt](https://guide.cryosparc.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://guide.cryosparc.com/processing-data/automated-workflows/downloads-workflow-jsons-sample-volumes-and-masks.md).

# Downloads: Workflow JSONs, sample volumes, and masks

## Workflow v1

This Workflow v1 was tested using 21 GPCR datasets. The development of the Workflow is described here: 

{% content-ref url="/pages/qk7066CloymhjPPxRlSO" %}
[Full automated data processing: a case study using GPCRs](/processing-data/automated-workflows/full-automated-data-processing-a-case-study-using-gpcrs.md)
{% endcontent-ref %}

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Read the entire preprint here: [End-to-end automation of repeat-target cryo-EM structure determination in CryoSPARC](https://doi.org/10.1101/2025.10.17.682689)
{% endhint %}

Below we provide a link to download a .zip archive containing CryoSPARC Workflow `JSON` files and required inputs which can be imported into CryoSPARC v4.7.1+ and used to process GPCR datasets like the ones we have tested. Two versions of the Workflow file are provided: one that processes raw movies directly from import, and another that processes micrographs that are generated after pre-processing in CryoSPARC Live. Please refer to the [**preprint**](https://www.biorxiv.org/content/10.1101/2025.10.17.682689v1) for details.

{% hint style="success" icon="link" %}
Download Workflow v1 files: [**automated\_workflow\_materials\_v1.zip**](https://structura-assets.s3.us-east-1.amazonaws.com/automated-workflows/Automated_workflow_materials_v1.zip)
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## Workflow v2

We've continued refining and simplifying the above workflow, and now we've [put it to the test on nine datasets of CDK-activating Kinase (CAK)](https://guide.cryosparc.com/processing-data/automated-workflows/advanced-automated-data-processing-a-case-study-using-cak) where we overcome severe preferred orientation resulting in maps with little to no anisotropy. Below you will find the workflow `JSON` file, the reference volume, and the junk volumes used in this case study. Additionally, the resulting maps and models from the automated data processing of CAK are available for download.

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Download Workflow v2 files: [**automated\_workflow\_materials\_v2.zip**](https://structura-assets.s3.us-east-1.amazonaws.com/automated-workflows/Automated_workflow_materials_v2.zip)
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Download CAK automation results: [**CAK\_automation\_maps\_models.zip**](https://structura-assets.s3.us-east-1.amazonaws.com/automated-workflows/CAK_automation_maps_models.zip)
{% endhint %}