This Guide contains detailed information on installing, configuring and using cryoSPARC v0.2.47 to 0.6.5. For detailed documentation, installation instructions and a tutorial for cryoSPARC v2.0+, please visit our new documentation page at cryosparc.com/docs. We highly recommend upgrading to v2.0 to take advantage of the full pipeline for processing single particle cryo-EM data, as well as powerful new workflow features.

Introduction

Cryo-EM Single Parcticle Ab initio Reconstruction and Classification (cryoSPARC)

CryoSPARC is a software package for processing single-particle electron cryo-microscopy (cryo-EM) data.

  • For more information, visit cryosparc.com and structura.bio, or follow us on Twitter (@structurabio).
  • Our blog has the latest insights on cryo-EM data processing and getting the most out of cryoSPARC.
  • Troubleshooting and tips? See the Discussion Forum.
  • Log errors, issues and feature requests on the Issue Tracker.