CryoSPARC Guide

Data Processing Tutorials

Tutorials on how to use CryoSPARC jobs and processing cryo-EM data.

Introduction to CryoSPARC

Case Studies

Data Processing

Alongside these tutorials, see: All Job Types in CryoSPARC and Tutorial Videos

Files, Data and Import


Particle Picking

Ab-initio Reconstruction

Case Study: Previously unknown conformation of AAA+ unfoldase discovered using cryoSPARC

Helical Reconstruction

3D Refinement

Local Refinement

Conformational Variability