Job: 3D Flexible Refinement (3DFlex) (BETA)

3D Flexible Refinement (3DFlex) is a motion-based deep generative model for continuous heterogeneity. It can model non-rigid motion and flexibility of a protein molecule across its conformational landscape, and can use the motion model to combine signal from particle images in different conformations to improve refinement resolution in flexible regions.

For more details on this job, available in CryoSPARC v4.1+, please see:

Tutorial: 3D Flexible RefinementTutorial: 3D Flex Mesh Preparation