# Interactive Job: Manual Picker

{% hint style="warning" %}
The information in this section applies to CryoSPARC ≤v3.3. For CryoSPARC v4.0+, please see:[Interactive Jobs](/application-guide/interactive-jobs.md)
{% endhint %}

## **Description**

* Manually pick particles interactively from micrographs.

## **Input**

* Aligned/motion-corrected micrographs

## **Common Parameters**

* Once the job is running, you can input and adjust the `Box size` in the job inspector/stream log. We recommend a box size that is at least double the diameter of the particle.
* You can also adjust the `Contrast Intensity Override` slider to manually select the contrast bounds when viewing a micrograph.

## **Output**

* Particles

## **Notes and Limitations**

When manually picking particles with the goal of creating a template for auto-picking, we recommend picking particles from multiple micrographs with a range of defocus and CTF fit values to ensure a comprehensive template.

Manual picking is the most time consuming picking method. As such, this job is recommended for picking a small subset of micrographs for the purposes of providing initial picks to template picking and/or deep picking instead of picking entire datasets.

## **Common Next Steps**

* 2D Classification and Select 2D to generate templates for Template picking


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