CryoSPARC Guide

Job: Downsample Particles

Downsample particles to save space.


Downsample particles and save them with smaller box sizes and optionally apply filters.
Downsample particles outputs depicting original and processed particles


  • Particles

Common Parameters

  • Fourier crop to box size (pix): size of outputs bins after downsampling
  • Lowpass resolution (A): Resolution of corner frequency in Angstroms


  • Downsampled Particles

Common Next Steps

  • Running 2D Classification, 3D Classification, 3D Variability Analysis or Heterogeneous Refinement on downsampled particles. To refine a structure using the full particle resolution, you can reference the original (non-downsampled) particle data using an input-group override as described in this tutorial.